Signs and Symptoms - Gradual enlargement of major salivary glands, particularly parotid glands - Swelling may be on one side or both sides, causing disfigurement and pain - Xerostomia (dry mouth) without other causes such as medication side effects - HIV-SGD may be the presenting sign of HIV infection - Xerophthalmia (dry eyes) and arthralgia (joint pain) similar to Sjögren syndrome

Epidemiology - HIV-SGD is more prevalent in HIV positive children than HIV positive adults (19% and 1% respectively) - Unlike other oral manifestations of HIV/AIDS, HIV-SGD has increased despite the introduction of highly active antiretroviral therapy (HAART)

References - Burket LW; Greenberg MS; Michael Glick; Jonathan A Ship (2008). Burkets Oral Medicine. PMPH-USA. pp.207–208. ISBN978-1-55009-345-2. - Jeffers, L; Webster-Cyriaque, JY (April 2011). Viruses and salivary gland disease (SGD): lessons from HIV SGD. Advances in Dental Research. 23 (1): 79–83. doi:10.1177/0022034510396882. PMC3144046. PMID21441486. - Witt RL (1 January 2011). Salivary Gland Diseases: Surgical and Medical Management. Thieme. pp.60–61. ISBN978-1-60406-537-4. - Schiødt, M (February 1992). HIV-associated salivary gland disease: a review. Oral Surgery, Oral Medicine, and Oral Pathology. 73 (2): 164–7. doi:10.1016/0030-4220(92)90189-w. PMID1549310.

Prevalence in HIV Positive Children - HIV-SGD is more prevalent in HIV positive children than HIV positive adults (19% and 1% respectively)

Impact of HAART on HIV-SGD - Unlike other oral manifestations of HIV/AIDS, HIV-SGD has increased despite the introduction of highly active antiretroviral therapy (HAART)