Signs and Symptoms
- Warthin's tumor primarily affects individuals aged 60-70 years.
- There is a slight male predilection according to recent studies.
- The tumor is slow-growing and painless.
- It usually appears in the tail of the parotid gland near the angle of the mandible.
- In 5-14% of cases, Warthin's tumor is bilateral, but the two masses usually occur at different times.

Locations
- The parotid gland is the most likely affected gland.
- Warthin's tumor is virtually restricted to the parotid gland.
- It is the second most common benign parotid tumor after pleomorphic adenoma.
- The prevalence of Warthin's tumor is steadily increasing.

Cause
- The cause of Warthin's tumor is unknown.
- There is a strong association with cigarette smoking.
- Smokers are at 8 times greater risk of developing Warthin's tumor than the general population.

Diagnosis
- The appearance of Warthin's tumor under the microscope is unique.
- It is characterised by cystic spaces surrounded by two uniform rows of oncocytes.
- The cystic spaces have papillary infoldings of epithelium.
- The epithelium has lymphoid stroma with germinal center formation.
- The differential diagnosis includes sebaceous lymphadenoma and oncocytoma.

Treatment
- Most Warthin's tumors are treated with surgical removal called parotidectomy.
- Unlike pleomorphic adenoma, Warthin's tumor is non-recurrent.

Warthin's tumor (Wikipedia)

Warthin's tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers (lymph node-like stroma). It is named for pathologist Aldred Scott Warthin, who described two cases in 1929.

Warthin's tumor
Other namesWarthin tumour, monomorphic adenoma, adenolymphoma
Cytopathology of Warthin's tumor, with typical cellular features (and a relatively uncommon binucleated cell). Pap stain.
SpecialtyOncology Edit this on Wikidata
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