Signs and Symptoms - Similar to other malignant salivary gland tumors - Preceded by a long-standing mass - Mass does not appear to be growing - Rapid growth - Facial weakness (due to facial nerve compression) - Pain - Skin ulceration - Fixation of the mastoid tip - Paresthesias

Diagnosis - Diagnosed by examining under the microscope - Consideration of individual history - In 75% of cases, it arises in a pleomorphic adenoma - In 25% of cases, it is diagnosed based on the presence of a carcinoma and history of pleomorphic adenoma - Relative incidence of parotid tumors, showing carcinoma ex pleomorphic adenoma at right - Relative incidence of submandibular tumors, showing carcinoma ex pleomorphic adenoma at top-right

Related Topics - Salivary gland - Pleomorphic adenoma

References - Di Palma, S. (Jul 2013). Carcinoma ex pleomorphic adenoma, with particular emphasis on early lesions. Head Neck Pathol. 7 Suppl 1: S68-76. doi:10.1007/s12105-013-0454-z. PMC3712089. PMID23821206. - Antony, J.; Gopalan, V.; Smith, RA.; Lam, AK. (Mar 2012). Carcinoma ex pleomorphic adenoma: a comprehensive review of clinical, pathological and molecular data. Head Neck Pathol. 6 (1): 1–9. doi:10.1007/s12105-011-0281-z. PMC3311945. PMID21744105. - Steve C Lee, MD, PhD (22 December 2022). Salivary Gland Neoplasms. Medscape {{cite journal}}:CS1 maint: multiple names: authors list (link) Updated: Jan 13, 2021 Diagrams by Mikael Häggström, MD

External Links - Classification - Retrieved from https://en.wikipedia.org/w/index.php?title=Carcinoma_ex_pleomorphic_adenoma&oldid=1143201491 - Category: Glandular and epithelial neoplasia - Hidden categories: CS1: long volume value, CS1 maint: multiple names: authors list, Articles with short description, Short description matches Wikidata