Junctional Epithelium
- The junctional epithelium is a nonkeratinised stratified squamous epithelium.
- It lies immediately apical to the sulcular epithelium.
- The junctional epithelium attaches to the tooth surface via the epithelial attachment.
- The junctional epithelium can attach to enamel, cementum, or dentin.
- The junctional epithelium is derived from the reduced enamel epithelium during tooth development.
- The ameloblasts secrete a basal lamina on the tooth surface, which becomes part of the primary epithelial attachment.
- As the tooth erupts, the coronal part of the fused and surrounding epithelium peels back, leaving the cervical part attached to the tooth.
- This fused tissue near the cementoenamel junction serves as the initial junctional epithelium.
- The initial junctional epithelium is later replaced by a definitive junctional epithelium as the root is formed.
- The junctional epithelium has wide intercellular spaces and fewer desmosomal junctions to allow white blood cells to pass through.
- It is thinner than the sulcular epithelium, ranging from 15 to 30 cells thick at the floor of the gingival sulcus.
- The superficial cells of the junctional epithelium serve as part of the epithelial attachment.
- The junctional epithelium has a special structural framework and collaboration with nonepithelial cells to provide antimicrobial mechanisms.
- It does not have a keratinizing superficial layer, making it susceptible to microbial attack.
- Damage to the junctional epithelium can result in irregular texture and the formation of pocket epithelium within the periodontal pocket.
- The increased permeability of the junctional epithelium allows microorganisms and toxins to enter, leading to infection.
- Pathological changes include ulceration, gingival hyperplasia, rete ridges, connective tissue papillae, and increased exfoliation of epithelial cells.
- Inflammatory lesions can progress to the loss of bone and connective tissue attachment to the tooth.
- The junctional epithelium plays a role in the development and progression of periodontal disease.
Surface Morphology of Pocket Epithelium
- Published in Ultrastructural Pathology journal in 2005.
- Surface morphology refers to the physical characteristics of the pocket epithelium.
- The study found that the surface morphology of the pocket epithelium plays a role in the development of certain conditions.
- The article suggests that further research is needed to fully understand the implications of the surface morphology.
- The study was conducted by a team of researchers including Preston D. Miller, Willoughby D. Miller, Carl E. Misch, John Mankey Riggs, and Jay Seibert.
Capnocytophaga sp.
- Capnocytophaga sp. is a type of bacteria.
- The presence of Capnocytophaga sp. in the pocket epithelium may have implications for oral health.
- Further research is needed to understand the specific role of Capnocytophaga sp. in relation to the pocket epithelium.
- The study did not provide conclusive evidence on the effects of Capnocytophaga sp. on the pocket epithelium.
- Jørgen Slots and Paul Roscoe Stillman were part of the research team that investigated Capnocytophaga sp.
Ultrastructural Pathology Journal
- Ultrastructural Pathology is a scientific journal.
- The journal focuses on the study of cellular structures and their relation to diseases.
- The article on the surface morphology of pocket epithelium was published in this journal.
- The journal provides a platform for researchers to share their findings in the field of pathology.
- The study on the surface morphology of pocket epithelium was cited in the journal under the PMID16028668 reference.
Further Research and Implications
- The study on the surface morphology of pocket epithelium highlights the need for further research in this area.
- Understanding the surface morphology of pocket epithelium can contribute to the diagnosis and treatment of oral diseases.
- The findings of this study may have implications for periodontal disease management.
- The study suggests that the surface morphology of pocket epithelium may be a potential target for therapeutic interventions.
- The involvement of multiple researchers from different institutions indicates the significance of this research.