Liver Diseases
- Ground glass hepatocytes
- Primary biliary cirrhosis
- Budd–Chiari syndrome
- Micrograph of non-alcoholic fatty liver disease
- Fascioliasis, a parasitic infection caused by liver fluke
- Hepatitis, inflammation of the liver caused by viruses or toxins
- Alcoholic liver disease, a manifestation of alcohol overconsumption
- Fatty liver disease, reversible condition with fat accumulation in liver cells
- Non-alcoholic fatty liver disease, associated with obesity and metabolic syndrome
- Hereditary diseases causing liver damage, such as hemochromatosis and Wilson's disease
- Transthyretin-related hereditary amyloidosis, where mutated protein affects liver
- Gilbert's syndrome, a genetic disorder affecting bilirubin metabolism
- Cirrhosis, fibrosis formation in place of liver cells, causing chronic liver failure
- Primary liver cancer, including hepatocellular carcinoma and cholangiocarcinoma
- Primary biliary cirrhosis, a serious autoimmune disease of bile capillaries
- Primary sclerosing cholangitis, a chronic inflammatory disease of the bile duct
- Budd–Chiari syndrome, clinical picture caused by hepatic vein occlusion

Signs and Symptoms
- Jaundice
- Confusion and altered consciousness (hepatic encephalopathy)
- Thrombocytopenia and coagulopathy
- Risk of bleeding, especially in the gastrointestinal tract

Mechanisms
- Liver diseases develop through several mechanisms
- DNA damage is a shared mechanism in major liver diseases
- Viral infection increases reactive oxygen species and causes inflammation
- Alcohol consumption leads to DNA damage and oxidative stress
- Obesity increases pro-inflammatory cytokines and deoxycholic acid, causing DNA damage and inflammation in the liver

Other Relevant Aspects
- Several liver diseases are due to viral infections like Hepatitis B and C
- Vertical transmission of viral hepatitides can occur during birth
- High alcohol consumption can lead to alcoholic liver diseases and liver cancer
- Fat accumulation in liver cells and inflammation contribute to alcoholic liver disease
- Cirrhosis can develop in advanced stages of alcoholic liver disease

Air Pollutants
- Particulate matter and carbon black are common pollutants
- They have a direct toxic effect on the liver and cause inflammation
- Impact on lipid metabolism and fatty liver disease
- Translocation from lungs to the liver through extrapulmonary circulation
- Water-soluble fractions of particulate matter play a significant role in translocation

Liver disease (Wikipedia)

For Injuries associated with liver, see Liver injury.

Liver disease, or hepatic disease, is any of many diseases of the liver. If long-lasting it is termed chronic liver disease. Although the diseases differ in detail, liver diseases often have features in common.

Liver disease
Other names	Hepatic disease
A gross pathology specimen of liver metastases caused by pancreatic cancer
Specialty	Hepatology, gastroenterology
Types	Fatty liver disease, Hepatitis (and several more)
Diagnostic method	Liver function tests
Treatment	Depends on type(See types)