Structure of the olfactory tract - The olfactory tract and olfactory bulb are located in the olfactory sulcus. - The sulcus is formed by the medial orbital gyrus on the inferior surface of each frontal lobe. - Fibers of the olfactory tract appear to end in various regions, including the olfactory tubercle, anterior olfactory nucleus, prepyriform area, amygdala nuclei, and nucleus of the stria terminalis. - The olfactory tract divides posteriorly into a medial and a lateral stria. - Caudal to this is the olfactory trigone and the anterior perforated substance.
Medial olfactory stria - The medial olfactory stria turns medially behind the parolfactory area. - It ends in the subcallosal gyrus. - In some cases, a small intermediate stria is seen running backward to the anterior perforated substance.
Lateral olfactory stria - The lateral olfactory stria is directed across the lateral part of the anterior perforated substance. - It then bends abruptly medially toward the uncus of the parahippocampal gyrus.
Clinical significance of the olfactory tract - Destruction to the olfactory tract results in ipsilateral anosmia (loss of the ability to smell). - Anosmia, either total or partial, is a symptom of Kallmann syndrome, a genetic disorder affecting the development of the olfactory tract. - The depth of the olfactory sulcus can indicate congenital anosmia.
Additional information - Scheme of rhinencephalon, with the olfactory tract visible on the left. - Base of the brain. - Plan of olfactory neurons. - Orbital surface of frontal lobe olfactory sulcus shown in red. - References to relevant sources and studies. - External link to further information on cranial nerves.