Definition and Overview of Stafne Defect
- Stafne Defect is a bone cavity near the angle of the mandible
- It is also known as Stafne Bone Cavity or Static Bone Cyst
- The defect is usually asymptomatic and doesn't require treatment
- The condition is more common in males than females
- Stafne Defect is often discovered incidentally during dental imaging

Etiology and Pathogenesis of Stafne Defect
- Stafne Defect is believed to be a developmental anomaly
- It occurs due to a lingual cortical bone concavity near the mandibular angle
- The defect is caused by the displacement of the submandibular salivary gland
- Heterotopic salivary gland tissue can be found within the defect
- Stafne Defect is not associated with trauma or infection

Diagnosis and Imaging of Stafne Defect
- Diagnosis is typically made through radiographic imaging
- Panoramic radiographs are commonly used to identify the bone cavity
- Computed tomography (CT) scans can provide detailed information about the defect
- Magnetic resonance imaging (MRI) may be used to assess the soft tissue components
- Differential diagnosis includes other radiolucent lesions of the mandible

Clinical Significance and Management of Stafne Defect
- Stafne Defect is usually asymptomatic and doesn't require treatment
- Surgical intervention is not necessary unless there are complications
- Monitoring the defect through regular imaging is recommended
- If the defect causes aesthetic concerns or functional issues, surgical repair may be considered
- The risk of pathological fractures associated with Stafne Defect is extremely low

Research and Literature on Stafne Defect
- Stafne Defect was first described by Edward C. Stafne in 1942
- Several studies have reported cases of Stafne Defect with different variations
- The prevalence of Stafne Defect ranges from 0.08% to 0.26% in various populations
- Research has explored the radiographic characteristics and variations of the defect
- The etiology and pathogenesis of Stafne Defect are still not fully understood

Stafne defect (Wikipedia)

The Stafne defect (also termed Stafne's idiopathic bone cavity, Stafne bone cavity, Stafne bone cyst (misnomer), lingual mandibular salivary gland depression, lingual mandibular cortical defect, latent bone cyst, or static bone cyst) is a depression of the mandible, most commonly located on the lingual surface (the side nearest the tongue). The Stafne defect is thought to be a normal anatomical variant, as the depression is created by ectopic salivary gland tissue associated with the submandibular gland and does not represent a pathologic lesion as such. This cavity is commonly observed on panoramic radiograph.

Dental panoramic radiograph showing Stafne defect in the right mandible, below the inferior alveolar nerve canal (arrowed, appears on lower left of image). This x-ray was taken for an unrelated assessment of wisdom teeth, and the Stafne defect was a chance finding.
Axial computed tomograph of the same person. The Stafne defect appears as a well corticated 1 cm round defect in the medial cortex of the mandible in the right angle of the jaw (arrowed).
Coronal computed tomograph of the same person (Stafne defect arrowed).
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