Signs and Symptoms
- Similar to other malignant salivary gland tumors
- Preceded by a long-standing mass
- Mass does not appear to be growing
- Rapid growth
- Facial weakness (due to facial nerve compression)
- Pain
- Skin ulceration
- Fixation of the mastoid tip
- Paresthesias
Diagnosis
- Diagnosed by examining under the microscope
- Consideration of individual history
- In 75% of cases, it arises in a pleomorphic adenoma
- In 25% of cases, it is diagnosed based on the presence of a carcinoma and history of pleomorphic adenoma
- Relative incidence of parotid tumors, showing carcinoma ex pleomorphic adenoma at right
- Relative incidence of submandibular tumors, showing carcinoma ex pleomorphic adenoma at top-right
Related Topics
- Salivary gland
- Pleomorphic adenoma
References
- Di Palma, S. (Jul 2013). Carcinoma ex pleomorphic adenoma, with particular emphasis on early lesions. Head Neck Pathol. 7 Suppl 1: S68-76. doi:10.1007/s12105-013-0454-z. PMC3712089. PMID23821206.
- Antony, J.; Gopalan, V.; Smith, RA.; Lam, AK. (Mar 2012). Carcinoma ex pleomorphic adenoma: a comprehensive review of clinical, pathological and molecular data. Head Neck Pathol. 6 (1): 1–9. doi:10.1007/s12105-011-0281-z. PMC3311945. PMID21744105.
- Steve C Lee, MD, PhD (22 December 2022). Salivary Gland Neoplasms. Medscape {{cite journal}}:CS1 maint: multiple names: authors list (link) Updated: Jan 13, 2021 Diagrams by Mikael Häggström, MD
External Links
- Classification
- Retrieved from https://en.wikipedia.org/w/index.php?title=Carcinoma_ex_pleomorphic_adenoma&oldid=1143201491
- Category: Glandular and epithelial neoplasia
- Hidden categories: CS1: long volume value, CS1 maint: multiple names: authors list, Articles with short description, Short description matches Wikidata
Carcinoma ex pleomorphic adenoma (ca ex PA) is a type of cancer typically found in the parotid gland. It arises from the benign tumour pleomorphic adenoma.
| Carcinoma ex pleomorphic adenoma | |
|---|---|
 | |
| Micrograph of a carcinoma ex pleomorphic adenoma. The carcinoma component is on the lower right of the image. Benign parotid gland is seen at the left and pleomorphic adenoma is seen at the upper right. H&E stain. | |
| Specialty | Oncology |
Its prognosis depends on the stage. Early tumours have essentially a benign behaviour.
