Junctional Epithelium
- The junctional epithelium is a nonkeratinized stratified squamous epithelium.
- It lies immediately apical to the sulcular epithelium.
- The junctional epithelium attaches to the tooth surface via the epithelial attachment.
- The junctional epithelium can attach to enamel, cementum, or dentin.
- The junctional epithelium is derived from the reduced enamel epithelium during tooth development.
- The ameloblasts secrete a basal lamina on the tooth surface, which becomes part of the primary epithelial attachment.
- As the tooth erupts, the coronal part of the fused and surrounding epithelium peels back, leaving the cervical part attached to the tooth.
- This fused tissue near the cementoenamel junction serves as the initial junctional epithelium.
- The initial junctional epithelium is later replaced by a definitive junctional epithelium as the root is formed.
- The junctional epithelium has wide intercellular spaces and fewer desmosomal junctions to allow white blood cells to pass through.
- It is thinner than the sulcular epithelium, ranging from 15 to 30 cells thick at the floor of the gingival sulcus.
- The superficial cells of the junctional epithelium serve as part of the epithelial attachment.
- The junctional epithelium has a special structural framework and collaboration with nonepithelial cells to provide antimicrobial mechanisms.
- It does not have a keratinizing superficial layer, making it susceptible to microbial attack.
- Damage to the junctional epithelium can result in irregular texture and the formation of pocket epithelium within the periodontal pocket.
- The increased permeability of the junctional epithelium allows microorganisms and toxins to enter, leading to infection.
- Pathological changes include ulceration, gingival hyperplasia, rete ridges, connective tissue papillae, and increased exfoliation of epithelial cells.
- Inflammatory lesions can progress to the loss of bone and connective tissue attachment to the tooth.
- The junctional epithelium plays a role in the development and progression of periodontal disease.

Surface Morphology of Pocket Epithelium
- Published in Ultrastructural Pathology journal in 2005.
- Surface morphology refers to the physical characteristics of the pocket epithelium.
- The study found that the surface morphology of the pocket epithelium plays a role in the development of certain conditions.
- The article suggests that further research is needed to fully understand the implications of the surface morphology.
- The study was conducted by a team of researchers including Preston D. Miller, Willoughby D. Miller, Carl E. Misch, John Mankey Riggs, and Jay Seibert.

Capnocytophaga sp.
- Capnocytophaga sp. is a type of bacteria.
- The presence of Capnocytophaga sp. in the pocket epithelium may have implications for oral health.
- Further research is needed to understand the specific role of Capnocytophaga sp. in relation to the pocket epithelium.
- The study did not provide conclusive evidence on the effects of Capnocytophaga sp. on the pocket epithelium.
- Jørgen Slots and Paul Roscoe Stillman were part of the research team that investigated Capnocytophaga sp.

Ultrastructural Pathology Journal
- Ultrastructural Pathology is a scientific journal.
- The journal focuses on the study of cellular structures and their relation to diseases.
- The article on the surface morphology of pocket epithelium was published in this journal.
- The journal provides a platform for researchers to share their findings in the field of pathology.
- The study on the surface morphology of pocket epithelium was cited in the journal under the PMID16028668 reference.

Further Research and Implications
- The study on the surface morphology of pocket epithelium highlights the need for further research in this area.
- Understanding the surface morphology of pocket epithelium can contribute to the diagnosis and treatment of oral diseases.
- The findings of this study may have implications for periodontal disease management.
- The study suggests that the surface morphology of pocket epithelium may be a potential target for therapeutic interventions.
- The involvement of multiple researchers from different institutions indicates the significance of this research.

The junctional epithelium (JE) is that epithelium which lies at, and in health also defines, the base of the gingival sulcus. The probing depth of the gingival sulcus is measured by a calibrated periodontal probe. In a healthy-case scenario, the probe is gently inserted, slides by the sulcular epithelium (SE), and is stopped by the epithelial attachment (EA). However, the probing depth of the gingival sulcus may be considerably different from the true histological gingival sulcus depth.

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